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LONG HALF-LIFE RECOMBINANT BUTYRYLCHOLINESTERASE

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专利名称:LONG HALF-LIFE RECOMBINANT

BUTYRYLCHOLINESTERASE

发明人:HUANG, YUE,WILGUS, HARVEY申请号:EP07811030申请日:20070802公开号:EP2049661A4公开日:20120704

摘要:The present invention provides for butyrylcholinesterase (BChE) attached topolyethylene glycol (PEG) to form a complex having greatly increased mean residencetime (MRT) in the system of an animal following injection thereinto. Also disclosed arecompositions of such complexes, methods of preparing these complexes and method forusing these complexes and compositions in the treatment and/or prevention of toxiceffects of poisons, such as neurotoxins, to which said animals, such as humans, have been,or may become, exposed.

申请人:PHARMATHENE INC.

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