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Peptides presented by cells

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专利名称:Peptides presented by cells发明人:Francis J. Carr,Graham Carter,Koen

Hellendoorn

申请号:US10343443申请日:20030131

公开号:US20030171290A1公开日:20030911

摘要:The present invention relates to methods to determine peptides presented onthe surface of mammalian cells following addition to the cells of a protein. The presentinvention also relates to diagnostic tests based on the determination of such peptides ormodified molecules resulting from determination of such peptides, such aspharmaceutical entities preferably having specific biological activity and reduced orenhanced immunogenicity when compared with the corresponding non-modified

molecules. The methods according to this invention are preferably established with toolsusing mass spectroscopy (MS).

申请人:CARR FRANCIS J.,CARTER GRAHAM,HELLENDOORN KOEN

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